Application

Immunocytochemsitry Analysis: A 1:50 dilution of this antibody detected SOX-15 in a undifferentiated H9 human embryonic stem cells.

Research CategoryStem Cell Research

Anti-SOX-15 Antibody, clone 1A2.1 is an antibody against SOX-15 for use in western blotting & ICC.

Research Sub CategoryPluripotent & Early Differentiation

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Members of the SOX family of transcription factors are widely conserved and play important roles in early development and are often used as markers to assess the differentiation of specific cell lineages. SOX-15 (also known as SOX-20) is a nuclear, 25 kDa transcriptional repressor that belongs to group G of the SOX gene family. Sox-15 is widely expressed in fetal and adult tissues, with highest level found in fetal spinal cord, adult brain and adult testis. Recently, SOX-15 has been identified as having transcriptional control in mouse embryonic stem cells pluripotency along with SOX-2. SOX-15 is also expressed in myoblasts and regulates skeletal muscle regeneration and differentiation.

Immunogen

GST-tagged recombinant protein corresponding to human SOX-15.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blotting in a undifferentiated H9 human embryonic stem cell lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected SOX-15 in a undifferentiated H9 human embryonic stem cells.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~ 36 kDa observed